Pure Encapsulations | DIM Detox

Detox Support & Hormone Metabolism Formula: Vegan & Science-Backed. DIM Detox provides 25 mg per serving of a highly absorbable form of diindolylmethane (BioResponse DIM®), an essential metabolite of indole-3-carbinol. These compounds promote healthy estrogen metabolism and cell cycle activity.

 

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Primary Benefits

  • Supports phase II detoxification enzyme activity

  • Enhances healthy hormone detoxification through the glucuronidation pathway

  • Promotes healthy estrogen metabolism and cell cycle activity

  • Lignans provide support for cellular, heart, breast, bone, and cognitive health

  • Offers antioxidant support for cellular protection

  • Contains BioResponse DIM® diindolylmethane complex

  • Includes broccoli sprout concentrate (whole plant)

  • Made with high-quality vegan ingredients backed by verifiable science

Dietary Considerations

  • Gluten-Free

  • Vegetarian

  • Vegan

  • Non-GMO

Product Details

  • The glucosinolates in broccoli, including indole-3-carbinol and sulforaphane, help support healthy detoxification.

  • BioResponse DIM® provides 25 mg per serving of a highly absorbable form of diindolylmethane, an essential metabolite of indole-3-carbinol. These compounds promote healthy estrogen metabolism and cell cycle activity.

  • Calcium-D-glucarate targets beta-glucuronidase enzyme activity, promoting healthy hormone detoxification through the glucuronidation pathway.3 Lignans, such as 7-hydroxymatairesinol (HMR), are converted in the body to enterolactone.

  • Research indicates that dietary intake of lignans and healthy serum enterolactone levels provide support for cellular, heart, breast, bone, and cognitive health.

  • Silymarin, alpha lipoic acid, and N-acetyl-L-cysteine (NAC) support phase II detoxification enzyme activity in the liver and offer antioxidant support for cellular protection.

  • Taurine, glycine and methionine promote phase II detoxification pathways and healthy cell metabolism.

Suggested Use

  • As a dietary supplement, take 2 capsules per day, with meals.

Warnings

  • If pregnant or lactating, consult your physician before taking this product. At this time, there are no known side effects or precautions. Consult your physician for more information.

  • Keep out of the reach of children.

  • Store in a cool, dry place. Use only if the safety seal is intact.

References:

  1. Ferenci, P., Dragosics, B., Dittrich, H., Frank, H., Benda, L., Lochs, H., Meryn, S., Base, W., & Schneider, B. (1989). Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver. Journal of Hepatology, 9(1), 105–113. https://doi.org/10.1016/0168-8278(89)90083-4

  2. Flier, J., Van Muiswinkel, F. L., Jongenelen, C. A. M., & Drukarch, B. (2002). The neuroprotective antioxidant alpha-lipoic acid induces detoxication enzymes in cultured astroglial cells. Free Radical Research, 36(6), 695–699. https://doi.org/10.1080/10715760290029155

  3. Kang, W., & Kudsk, K. A. (2007). Is there evidence that the gut contributes to mucosal immunity in humans? JPEN. Journal of Parenteral and Enteral Nutrition, 31(3), 246–258. https://doi.org/10.1177/0148607107031003246

  4. Lebensburger, J. D., Aban, I., Pernell, B., Kasztan, M., Feig, D. I., Hilliard, L. M., & Askenazi, D. J. (2019). Hyperfiltration during early childhood precedes albuminuria in pediatric sickle cell nephropathy. American Journal of Hematology, 94(4), 417–423. https://doi.org/10.1002/ajh.25390

  5. Michnovicz, J. J. (1998). Increased estrogen 2-hydroxylation in obese women using oral indole-3-carbinol. International Journal of Obesity and Related Metabolic Disorders: Journal of the International Association for the Study of Obesity, 22(3), 227–229. https://doi.org/10.1038/sj.ijo.0800573

  6. Riby, J. E., Chang, G. H., Firestone, G. L., & Bjeldanes, L. F. (2000). Ligand-independent activation of estrogen receptor function by 3, 3’-diindolylmethane in human breast cancer cells. Biochemical Pharmacology, 60(2), 167–177. https://doi.org/10.1016/s0006-2952(00)00307-5

  7. Rodriguez-Leyva, D., Weighell, W., Edel, A. L., LaVallee, R., Dibrov, E., Pinneker, R., Maddaford, T. G., Ramjiawan, B., Aliani, M., Guzman, R., & Pierce, G. N. (2013). Potent antihypertensive action of dietary flaxseed in hypertensive patients. Hypertension (Dallas, Tex.: 1979), 62(6), 1081–1089. https://doi.org/10.1161/HYPERTENSIONAHA.113.02094

  8. Spence, J. D., Thornton, T., Muir, A. D., & Westcott, N. D. (2003). The effect of flax seed cultivars with differing content of alpha-linolenic acid and lignans on responses to mental stress. Journal of the American College of Nutrition, 22(6), 494–501. https://doi.org/10.1080/07315724.2003.10719327

  9. Thompson, L. U., Chen, J. M., Li, T., Strasser-Weippl, K., & Goss, P. E. (2005). Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research, 11(10), 3828–3835. https://doi.org/10.1158/1078-0432.CCR-04-2326

 
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